Andria Farrens Research
fMRI Research
Functional Connectivity
In this work, we looked at changes in neural activity following a motor task without learning, and compared it to changes following learning in a constant force task. We had participants return 24 hours later and perform a task in the same constant force condition, to quantify how much they retained of the previous training (i.e. behavioral evidence that motor memories were formed). We then investigated changes in neural activity across each task, and their relationship to learning and retention to identify pathways associated with motor memory formation.
Following the learning task (dynamic adaptation), rsFC increased within the cortico-cerebellar network and decreased interhemispherically within the cortical sensorimotor network. Results here show the group level change of task-localized motor regions of interest (left M1, PM, S1) to whole brain resting state functional connectivity following dynamic adaptation task performance (REST3-REST1). All statistical parametric maps are overlaid on axial slices of the standard Montreal Neurologic Institute 152 template, with reported z coordinates in mm. For each ROI, the seed-voxel level T-maps were thresholded at p-voxel-uncorrected < 0.001, p-cluster-FDR<0.05, resulting in |T(29)| >3.65, Kcluster>134.
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